A Brief History of Time - Stephen Hawking An amazing and fascinating documentary about Stephen Hawking's ideas from his book titled the same and about his life.
A Brief History of Time attempts to explain a range of subjects in cosmology, including the Big Bang, black holes, light cones and superstring theory, to the nonspecialist reader. Its main goal is to give an overview of the subject but, unusual for a popular science book, it also attempts to explain some complex mathematics. The author notes that an editor warned him that for every equation in the book the readership would be halved, hence it includes only a single equation: E = mc2. In addition to Hawking's abstinence from equations, the book also simplifies matters by means of illustrations throughout the text, depicting complex models and diagrams. In 1991, Errol Morris directed a documentary film about Hawking, but although they share a title, the film is a biographical study of Hawking, and not a filmed version of the book - and here it is;
Watch Documentary - A Brief History of Time - Prof. Stephen Hawking
Fun Notes;Before the book was published, an editor warned him that for every equation in the book the readership would be halved, hence it includes only a single equation: E = mc²
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Exploring the frontiers of Consciousness, creativity and the Brain - a discourse by Professor John Hagelin Phd. Professor Hagelin is one of the present day's Geniuses as far as understanding Consciousness from both scientific and Spiritual perspectives goes. Professor Hagelin is also a member of the Maharishi Foundation.
John Hagelin (born June 9, 1954) is an American scientist who was a researcher at the European Center for Particle Physics (CERN) and the Stanford Linear Accelerator Center (SLAC), is an educator and author, and has been the Natural Law Party candidate for President of the United States three times. Hagelin is Professor of Physics and Director of the Institute of Science, Technology and Public Policy at Maharishi University of Management, Executive Director of the International Center for Invincible Defense, President of the US Peace Government, Raja of Invincible America, and executive director of Global Financial Capital
Watch Lecture - Exploring the frontiers of Consciousness, creativity and the Brain
In 1981, Hagelin received his Ph.D. from Harvard, having already published five serious papers on particle theory. That same year, Hagelin won a postdoctoral research appointment at CERN (the European Center for Particle Physics) in Switzerland, and in 1983 was recruited by SLAC (the Stanford Linear Accelerator Center), CERN's North American counterpart.
In 1984, Hagelin shifted his appointment from SLAC to Maharishi International University (MIU), where he continued his research in physics, pursued a long-time interest in brain and cognitive science research, and established an accredited doctoral program in theoretical physics. Hagelin’s move to MIU in 1984 surprised and puzzled his colleagues. Howard Georgi and John Ellis tried to talk him out of it. But, according to Georgi, Hagelin "continued to do good physics anyway.” Nobel Laureate, Sheldon Glashow was quoted in a 1992 article as saying, “His papers are outstanding. We read them before he went to MIU and we read them now.” Hagelin remained in contact with colleagues from Harvard, Stanford, and CERN, and continued to collaborate with them. While at MIU, his contributions to the field of theoretical physics were supported by funding from the National Science Foundation.
Currently, Hagelin teaches physics as Professor of Physics at Maharishi University of Management (formerly MIU) and serves as Director of the Institute of Science, Technology and Public Policy at that institution. Hagelin is also identified as the Founding President of Maharishi Central University, which was announced in 2007. Central University was under construction in Smith Center, Kansas at the site of a previously-announced Peace Palace until early 2008, when, according to Hagelin, the project was put on hold while the TM Organization dealt with the death of the Maharishi.
In 1987 and 1989, Hagelin published two papers in the MUM's Journal of Modern Science and Vedic Science on the relationship between physics and consciousness.These papers discuss the Vedic understanding of consciousness as a field and compare it with theories of the unified field derived by modern physics. Hagelin argues that these two fields have almost identical properties and quantitative structure, and he presents other theoretical and empirical arguments that the two fields are actually one and the same—specifically, that the experience of unity at the basis of the mind achieved during the meditative state is the subjective experience of the very same fundamental unity of existence revealed by unified field theories.
Part of the evidence Hagelin presents for this explanation is the body of research on the effects that practitioners of the Transcendental Meditation technique and of the more advanced TM-Sidhi program (which includes a practice called "Yogic Flying") have on measured parameters in society. This phenomenon is called the "Maharishi Effect". In these two papers he cites numerous studies of such effects, and in the summer of 1993, he himself conducted a large scale study of this type. Hagelin recruited approximately 4,000 TM-Sidhi program practitioners to the Washington D.C. area, where they practiced the TM Sidhi techniques twice daily in a group. Using data obtained from the District of Columbia Metropolitan Police Department for 1993 and the preceding five years (1988–1992), Hagelin and collaborators followed the changes in crime rates for the area before, during, and after the 6 weeks the group was gathered in Washington DC. In 1999, the study, which showed a highly statistically significant drop in predicted crime, controlling for effects of temperature changes, was published in Social Indicators Research. Critique;
Physicist Victor J. Stenger wrote in The Humanist that John Hagelin talks about "quantum consciousness" and that quantum consciousness is a "myth" that "should take its place along with gods, unicorns, and dragons as yet another product of the fantasies of people unwilling to accept what science, reason, and their own eyes tell them about the world."
Peter Woit writes in his book, Not Even Wrong: The Failure of String Theory And The Search For Unity In Physical Law, that "Virtually every theoretical physicist in the world" rejects Hagelin's attempt to identify the "unified field" of superstring theory with the Maharishi's "unified field of consciousness" as "utter nonsense, and the work of a crackpot"
Awards; In 1992, Hagelin was honored with a Kilby International Award for his work in particle physics leading to the development of supersymmetric grand unified field theories, for his innovative applications of advanced principles from control systems theory and optimization theory to digital sound reproduction, and for his research on human consciousness. Chris Anderson questioned the value of the award in an article about Hagelin published in Nature.
In 1994, Hagelin was selected for the Ig Nobel Prize for Peace, an annual parody award given for achievements that “first make people laugh and then make them think." The award was given for the experimental conclusions drawn from the Washington, D.C. study.
Creativity: The Mind, Machines, and Mathematics: A Public Debate November 30, 2006 Running Time: 0:59:10 About the Lecture Two of the sharpest minds in the computing arena spar gamely, but neither scores a knockdown in one of the oldest debates around: whether machines may someday achieve consciousness. (NB: Viewers may wish to brush up on the work of computer pioneer Alan Turing and philosopher John Searle in preparation for this video.)
Ray Kurzweil confidently states that artificial intelligence will, in the not distant future, “master human intelligence.” He cites the “exponential power of growth in technology” that will enable both a minute, detailed understanding of the human brain, and the capacity for building a machine that can at least simulate original thought. The “frontier” such a machine must cross is emotional intelligence—“being funny, expressing loving sentiment…” And when this occurs, says Kurzweil, it’s not entirely clear that the entity will have achieved consciousness, since we have no “consciousness detector” to determine if it is capable of subjective experiences.
Acknowledging that his position will prove unpopular, David Gelernter launches his attack: “We won’t even be able to build super-intelligent zombies unless we approach the problem right.” This means admitting that a continuum of cognitive styles exists among humans. As for building a conscious machine, he sees no possibility of one emerging from even the most sophisticated software. “Consciousness means the presence of mental states strictly private with no visible functions or consequences. A conscious entity can call on a thought or memory merely to feel happy, be inspired, soothed, feel anger…” Software programs, by definition, can be separated out, peeled away and run in a logically identical way on any computing platform. How could such a program spontaneously give rise to “a new node of consciousness?”
Kurzweil concedes the difficulty of defining consciousness, but does not want to wish away the concept, since it serves as the basis for our moral and ethical systems. He maintains his argument that reverse engineering of the human brain will enable machines that can act with a level of complexity, from which somehow consciousness will emerge.
Gelernter replies that believing this “seems a completely arbitrary claim. Anything might be true, but I don’t see what makes the claim plausible.” Ultimately, he says, Kurzweil must explain objectively and scientifically what consciousness is -- “how it’s created and got there.” Kurzweil stakes his claim on our future capacity to model digitally the actions of billions of neurons and neurotransmitters, which in humans somehow give rise to consciousness. Gelernter believes such a machine might simulate mental states, but not actually pass muster as a conscious entity. Ultimately, he questions the desirability of building such computers: “We might reach the state some day when we prefer the company of a robot from Walmart to our next-door neighbor or roommates.”
Cognitive Neuroscience of Aging
Review
"This is an ambitious undertaking...chapters dense in information, but actually it works..."--The Psychologist "This excellent book marks the advent of a new discipline, the cognitive neuroscience of aging. It comprehensively covers measurement tools, empirical findings, and theoretical models. Editors and authors are leading scholars of this evolving discipline. I highly recommend this book to everyone interested in the intriguing dynamic between brain and cognition in old age." -Ulman Lindenberger, Professor of Psychology, Max Planck Institute for Human Development and Director, Center for Lifespan Development "This is the right book, by the right authors, at the right time. The editors have assembled most of the leading investigators taking a neuroscience approach to the study of cognitive aging, and have asked them to write integrative reviews of the existing literature and to speculate about productive directions for future research. The result is not only a compendium of, in the editors' words "state-of-the-art knowledge about the cognitive neuroscience of aging in 2004," but a valuable source of ideas for research over the next 5 to 10 years." -Timothy Salthouse, Brown-Forman Professor of Psychology, University of Virginia
Product Description Until very recently, what we knew about the neural basis of cognitive aging was based on two disciplines that had very little contact with each other. Whereas the neuroscience of aging investigated the effects of aging on the brain independently of age-related changes in cognition, the cognitive psychology of aging investigated the effects of aging on cognition independently of age related changes in the brain. Because an increasing number of studies have focused on the relationships between cognitive aging and cerebral aging, these two disciplines have begun to interact. This rapidly growing body of research has come to constitute a new discipline: cognitive neuroscience of aging. The goal of this book is to introduce this new discipline at a level that is useful to both professionals and students in cognitive neuroscience, cognitive psychology, neuroscience, neuropsychology, neurology, and related areas. The book is divided into four main sections. The first section describes noninvasive measures of cerebral aging, including structural (e.g., volumetric MRI), chemical, (e.g., dopamine PET), electrophysiological (e.g., ERP's), and hemodynamic measures (e.g. fMRI), and discusses how they can be linked to behavioral measures of cognitive aging. The second section reviews evidence for the effects of aging on neural activity during different cognitive functions, including perception and attention, use of imagery, working memory, long-term memory, and prospective memory. The third section focuses on clinical and applied concerns, such as the distinction between health aging and aging with Alzheimer's disease, and the use of cognitive training to ameliorate age-related cognitive decline. The final section describes theories that relate cognitive and cerebral aging, including models accounting for functional neuroimaging evidence and models supported by computer simulations. Taken together, the chapters in this volume provide the first unified and comprehensive overview of the new discipline of cognitive neuroscience of aging.
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* Format: Kindle Edition * Print Length: 408 pages * Publisher: Oxford University Press, USA; 1 edition (October 22, 2004) * Sold by: Amazon Digital Services * Language: English * ASIN: B000TRH2RS
Opening Remarks - How the Brain Invents the Mind A lecture by Dr. Susan Hockfield Rebecca SaxePh.D. '03 June 6, 2009; Running Time: 1:39:22
About the Lecture In trying financial times, Susan Hockfield remains optimistic and committed to pursuing MIT’s massive, multi-year initiatives in energy and life sciences. She prefaces her “whirlwind” tour of MIT for an alumni audience by referencing the campus-wide relief at the change in presidential administrations, which promises to make science and engineering more central, and to make “MIT values more mainstream.” If it indeed becomes “cool to be smart,” Hockfield believes MIT can count on taking a prominent national role in research, policy and education.
One key area in which MIT hopes to make a major contribution is sustainable energy. The MIT Energy Initiative, two years old, brings together faculty and students across all disciplines to develop a portfolio of new technologies (although the focus seems increasingly to fall on solar). Campus interest is so intense that the Institute has committed to a minor in energy, and it’s seeking five new professorships in the area. The other major enterprise involves fusing biological sciences with engineering, especially in the study of cancer. At the new Koch Institute, cancer biologists and engineers have already made “fundamental discoveries underlying new targeted cancer drugs,” and they are hard at work decoding the disease, and devising new methods for diagnosis and treatment.
Hockfield also candidly describes the impact of the economic downturn on the Institute, acknowledging that “most revenue streams have been compromised,” except for research. With the endowment down by 20-25%, departments across the board are making significant but strategic cuts for the next two to three years. MIT will not compromise on providing financial aid to needy students, a cost that understandably has risen in the past year, nor on hiring faculty. Hockfield hopes that private philanthropy will help MIT “preserve core strengths and values.” At the end of the recession, she says, “We want to come out with a leaner, stronger Institute.”
Fellow neuroscientist Rebecca Saxe outlines her research investigating the neural basis for a Theory of Mind -- how the human mind seems geared to “glean what others are thinking and feeling.” From her work with children and adults, Saxe has determined that there’s a very specific region of the brain -- the right temporal-parietal junction -- dedicated to thinking about how others think. This area lights up in the fMRI scanner when people read stories involving another person’s beliefs and moral judgments, but not when they digest other kinds of written material. The RTPJ develops this special function slowly (young children don’t have it), and Saxe has discovered that she can interfere with this region’s activities, altering her subjects’ sense of what constitutes morally permissible behavior. She’s exploring whether these distinct neural networks develop differently in children with autism, with the hope of finding therapies that might someday help treat the disorder.
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The Autistic Neuron A Lecture by Mark Bear; May 4, 2009 Running Time: 0:35:11
About the Lecture
This self-described “basic neuroscientist” confesses he never thought he’d give a talk on autism, but as Mark Bear recounts, decades of research in the basics are now paying off with important insights into the etiology and treatment of brain disorders, including autism.
Bear provides a primer on this developmental disorder, noting that its roots are biological, it is highly heritable, and astonishingly prevalent: one in 150 people express some of the symptoms of autism. These fall on a spectrum, from severely reduced social behavior, abnormal language, repetitive movements, seizures and mental retardation, to the milder Asperger’s Syndrome, where individuals are often academically successful, but socially awkward. Particularly significant to Bear: Autism’s underlying genetic changes manifest themselves in problematic communication between neurons.
To unravel autism, researchers are examining its clinical heterogeneity, “genetic risk architecture,” and how it alters brain connections and function. One of the difficulties in approaching autism is that a variety of genetic mutations can result in autistic behaviors, and only a few of these mutations have been identified. Bear himself has been probing the single gene disorder, Fragile X syndrome (responsible for about 5% of the cases “of full-blown autism.”) In Fragile X, the FMR1 gene is silenced, leading to a missing protein that serves as a key regulator of brain proteins involved in neuron communication. Without FMR1, “the brakes are missing,” and there’s excessive protein synthesis leading to altered brain function.
Bear hypothesized that it might be possible to correct Fragile X by bringing the system back in balance. He created mice models of the disease, and found that by reducing the number of neurotransmitter receptors that respond to the excessive brain proteins, he could ameliorate or correct Fragile X defects. These receptors are “druggable targets,” and, says Bear, “if the treatment works in fly, fish or mouse, it better work in humans or Darwin was wrong.”
Based on this work, drug companies are devising compounds to test in human clinical trials of Fragile X syndrome. In addition, Bear notes, colleagues have discovered that other mutations connected with autism also involve protein regulation problems. “This gets us excited, because it looks like a common pathway that causes synaptic dysfunction in different diseases that may ultimately manifest as autism. If that’s the case, then treatment for the disorder may be efficacious in multiple disorders.”
How the Brain Encodes Reward - a lecture by Okihide Hikosaka May 7, 2009 - Running Time: 0:51:02
About the Lecture As Ann Graybiel puts it, “basal ganglia were dark basement structures” until Okihide Hikosaka began his classic 1980s research demonstrating how these neuronal clusters influenced eye movements. Hikosaka has deepened and broadened his work in this once neglected area of the brain, and brings a McGovern audience up to date on his latest discoveries.
Hikosaka briefly sketches what is known about the basic pathways leading in, around and out of the basal ganglia, circuits that have been associated with stress, pain, mood, memory and arousal. This specialized cluster of neurons seems especially attuned to the neurotransmitter dopamine, and Hikosaka has been investigating “a number of unsolved questions,” including how dopamine neurons form circuits for movement control, whether such neurons encode “motivational values,” and what other parts of the brain guide them.
Hikosaka describes research demonstrating that certain dopamine neurons become excited if a visual cue indicates a future reward, and become inhibited with a visual cue indicating no reward. Dopamine also increases after an action delivers a reward and decreases when an action produces no reward. Research began to explore whether dopamine neurons “encode motivational values, including reward and punishment.” After others’ studies yielded contradictory or uncertain conclusions, Hikosaka designed a set of studies on monkeys involving classical Pavlovian conditioning, with juice rewards and air puffs as aversive stimuli.
Among Hikosaka’s findings: some dopamine neurons were excited primarily by positive, reward-predicting stimuli, others inhibited by air puff-predicting stimuli. But he also found another group of dopamine neurons excited both by positive and negative reward-predicting stimuli (as well as the stimuli themselves). Hikosaka posited two types of neurons that react in very different ways to motivational signals, which he described as value-coding and salience-coding. He also determined that the lateral habenula, a part of the brain sitting at one end of the thalamus, seems to regulate dopamine pathways involved in some motivational responses. By sending a weak electric pulse through the lateral habenula, Hikosaka saw a very strong inhibition of the dopamine neurons that “encode mostly motivational values.”
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Christopher C. Kraft Jr. November 8, 2005 Running Time: 2:00:32
About the Lecture Chris Kraft manages to present in a single event the ultimate in engineering case studies, as well as an insider’s history of 20th century space missions and a pep talk for Aero-Astro students. This blunt raconteur describes the challenges of the earliest space pioneers. His story begins with Project Mercury in the 1950s, whose space task group of 35 included eight secretaries. “We were capable people but didn’t know a damn thing about how to fly in space,” recalls Kraft. How would they communicate with a man in orbit, or assess his health? Most doctors thought when an astronaut left earth’s atmosphere, “he’d be a blithering idiot.” Air to ground communication in those days consisted of 20 words of teletype. “How do you make real time decisions in those circumstances?” muses Kraft. He proudly describes assembling the Mission Rules book, “probably the smartest thing we ever did,” which attempted to address all conceivable malfunctions on a space mission. This was an early example of systems engineering, says Kraft.
When President Kennedy challenged NASA to get a man on the moon by the end of the 1960s, “Chris Kraft did not know how to determine orbital mechanics from 30 seconds of radar at Cape Canaveral. I thought the president was a little daft.” Suddenly, there were a whole new set of problems, such as how to make sure a craft aimed at the moon did not just hit it. In the Gemini and then Apollo programs, Kraft’s team solved innumerable and breathtakingly difficult issues. “We did a lot of things by the seat of our pants because we didn’t know any other way. We did it by feel, by having seen the past and doing things the right way.”
Kraft has some harsh words for the current state of space exploration. He can’t countenance NASA’s abandoning the space shuttle. “We seem to have a great propensity in this country for building something wonderful, great and high performance and throwing it away….Golly, my mother would have gone bananas!” He believes that NASA could have made the shuttle much more efficient to fly, and used it as a key element in the new race back to the Moon and to Mars. Kraft doesn’t believe this program will get off the ground—mainly because NASA hasn’t built anything new in 25 years, “and they’ve forgotten what it takes to do it.” The next space mission, whatever it turns out to be, will depend on the current crop of young aerospace engineers. “Go do it, don’t be frightened to fail,” exhorts Kraft. “You learn more from your failures than from your successes.”
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